:: Volume 7, Issue 3 (Military Caring Sciences 2020) ::
MCS 2020, 7(3): 252-260 Back to browse issues page
The Seroprevalence of Toxoplasma Gondii in Patients with Type 2 Diabetes Mellitus: A Case-Control Study in Southwest Iran
Shahrzad Soltani1 , Sanaz Tavakoli2 , Mohammad Barati3 , Marzieh Pashmforosh4 , Masoud Foroutan *2
1- Ph.D. in Medical Parasitology, Assistant Professor, Abadan Faculty of Medical Sciences, Abadan, Iran.
2- Ph.D. Student of Medical Parasitology, Parasitology and Mycology Department, Faculty of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.
3- Ph.D. in Medical Parasitology, Assistant Professor, Infectious Diseases Research Center, Aja University of Medical Sciences, Tehran, Iran.
4- Ph.D. in Pharmacology, Assistant Professor, Behbahan Faculty of Medical Sciences, Behbahan, Iran.
Abstract:   (5511 Views)
Introduction: Toxoplasma gondii is an obligate intracellular parasite, which causes toxoplasmosis in humans and many warm-blooded vertebrates.
Objective: The present study aimed to determine the prevalence of T. gondii in patients with type 2 diabetes mellitus (T2DM) and control individuals in the southwest of Iran.
Materials and Methods: In this case-control study, 80 patients with T2DM and 100 healthy individuals referred to Taleghani hospital in Abadan city during the winter season. Anti-T. gondii IgG antibody was measured in sera of participants using enzyme-linked immunosorbent assay (ELISA). A questionnaire containing some demographic information and risk factors related to T. gondii infection was completed by each participant. Results were analyzed using SPSS software 20. P <0.05 were considered as statistically significant.
Results: About 72.5% of patients with T2DM and 29% of healthy subjects were found to be positive for IgG antibody. The difference was statistically significant (P<0.001). Among the risk factors, contact with cats in both cases (P<0.001) and control groups (P=0.045) and source of drinking water in the control group (P=0.048) were significantly associated with T. gondii infection. No significant association was observed between age, gender, place of residence, educational level and consuming raw or undercooked meat with T. gondii (P>0.05).
Discussion and Conclusion: Considering the high prevalence of T. gondii in patients with T2DM compared to healthy individuals, more attention should be paid to this high-risk group. It is suggested that these patients routinely be tested for this parasite.
 
Keywords: Abadan, Diabetes, ELISA, Iran, Prevalence, Toxoplasma gondii.
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Type of Study: Research | Subject: Special
Received: 2020/07/5 | Revised: 2021/06/1 | Accepted: 2020/08/23 | Published: 2020/12/30
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Research code: 98114
Ethics code: IR.BHN.REC.1399.008

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