Introduction: Reviews of the history of human warfare especially in recent wars, indicates that many countries access to the chemical, biological and nucler warfare secretly and apparently. In our country, Iraq government used Widely 92 time’s mustard gas against Iranians. We still witness its complications among victims of chemical weapons. The purpose of this study was to compare the attitudes, knowledge and skills of self protection in chemical warfare on freshman nursing students of the Army School of Nursing based on border and non-border of Location.

 Materials & Methods: This descriptive-analytic study was conducted on 78 Army University of Medical Sciences nursing students who had not received any military training in nursing in 2014, using census approach. Data collection included a researcher-made questionnaire. Its validity was determined by content validity method and its reliability by retest. Data was analyzed using descriptive and interpretive statistical tests and SPSS version 20. P<0/05 was considered significant.

 Results: Independent t-test do not indicate a significant difference between border and non-border location in terms of knowledge (P=0/62) and skills (p=0/76) (P>0/05). Independent t-test indicates a significant difference between border and non-border location in terms of attitude (P=0/49) (P<0/05). That boundary students have higher scores than students were borderline.

 Discussion & Conclusion: Results indicates no significant differences between the skill and knowledge protective measures in chemical warfare that returns to Information from social networking and media. The absence of war and not experience it, over the years of war and between generations can be attributed to other causes. While there were statistically significant differences between these groups of attitude and it can be due to formal and informal education in the years before entering college and also the stress and anxiety of living in border areas.