Introduction: According to the World Health Organization reports, road traffic accidents caused 30.3% of morbidity and 28.7% of deaths in worldwide. The purpose of this study is assessment age and sex character of traffic accidents victims in the Isfahan province during the year 2009.

 Materials and Methods: This study is a cross-sectional study, which conducted with using data recorded in accidents nationwide program in Isfahan in 2009. Injuries caused by traffic accidents in this study are divided into three categories that include injuries by car, motorcycle and pedestrian. In this study t-test, chi-square and ANOVA were used for data analysis.

 Results: During the study period, 31, 587 people were injured in a traffic accident, which (77.4%) was males and (22.6%) women. The sex ratio (male to female) was 3.43. Mean age of injured person in this study was 29.21±15.87, in men 28.8±15.45 and in women 30.63±17.15, this difference t was statically significant ((P<0.001).So, between type of traffic accident and gender, age, location of traffic accident Occurrence (urban and suburban), area of traffic accident was a significant relationship (P<0.001).

 Discussion and conclusion: Most of traffic accidents victims were the young men. More than half of the injury caused motorcycles and occurrence in young people in urban areas. So should pass strict laws and improve the culture to modify driving behaviors, particularly in motorcycle riders to reduce the incidence and injury of traffic accidents.