Introduction: Medication, especially injection drugs are one of the complex situations and high-risk medications in clinical processes that nurses face. Risk management is one of the recommended method to identify and prevent adverse events from drug errors. The purpose of this study was to evaluate the impact of risk management programs on Preparation of electrolyte concentration skills by nursing staff.

Materials and methods: In this experimental study, 50 nurses working in emergency departments that were involved in the process of medication, were selected through census in 2014, then randomly divided into control and test groups. The control group received the routine of the hospital and in the experimental group risk management program was implemented. Preparation of electrolyte concentration skills was examined by valid and reliable researcher check list. Data were collected in pre and post-test with SPSS software, version 21 descriptive and inferential statistics were analyzed.

Results: nurses’ skill in preparing the condensed electrolyte, before the intervention and control groups, was respectively 96.16±3.2 and 17.17±0.2, and in two weeks after the implementation of risk management programs was respectively 27.27±8.1 and 83.17±2.2. In the pre-test, independent t test, a significant difference was observed between the two groups in the nursing skills (P>0.05). While in the post-test, significant differences in scores between the experimental and control groups were nursing skills (P<0.001). Paired t-test, before and after the intervention, the experimental group showed a significant difference (P<0.001).

Discussion and Conclusion: The results showed the effectiveness of the risk management program. Implementation of risk management programs as a way to improve nurses’ skills in preparing the condensed electrolytes is recommended.