Introduction: Viral hemorrhagic fevers are a kind of zoonotic infectious diseases. They have clinical symptoms such as: fever, myalgia, weakness, paralysis, hemorrhage, and in some cases hypotension, shock and death. Among Viral hemorrhagic fevers, Ebola is the most terrible disease.

Objectives: The purpose of this research was a review of studies on the causes of hemorrhagic fevers outbreaks and epidemics regarding Ebola and Crimean-Congo hemorrhagic fevers.

Materials and Methods: This was a review study based on internal and external search in databases such as PubMed, Google Scholar and SID, as well as search sites of WHO and CDC from 2001 to 2016.

Results: In this paper, two important diseases of hemorrhagic fever, Ebola and Crimean Congo, have been explained. It also talks about the biggest epidemic of Ebola in its history in the recent years as well as Crimean Congo hemorrhagic fever as an endemic disease in Iran. A number of people die from Crimean Congo hemorrhagic fever annually in Iran.

Discussion and Conclusion: The agents of hemorrhagic fevers are important for public health. These agents have the ability to extensively spread in natural outbreaks. They infect a mass population, and a large number of patients are health care providers. For success in controlling the outbreak of hemorrhagic fevers, it needs to interrupt the cycle of transmission. Therefore, self-protection education among health care providers is very important.