|
Identification of Neisseria Meningitidis Serogroups in Students Living in the Dormitory of Baqiyatullah University of Medical Sciences before and after Vaccination in 2019
|
Mehdi Masih Abadi1    , Rahim Sorouri2 , Ali Tavana3 , Ramezan Ali Ataee3 , Mojtaba Sepandi4 , Mojtaba Mahabadi *5 |
1- MSc in Microbiology, Medical Microbiology Department, School of Medicine, Baqiyatallah University of Medical Sciences, Tehran, Iran
2- Ph.D.in Bacteriology, Professor, Medical Microbiology Department, School of Medicine, Baqiyatallah University of Medical Sciences, Tehran, Iran
3- Ph.D. in Microbiology, Professor, Medical Microbiology Department, School of Medicine, Baqiyatallah University of Medical Sciences, Tehran, Iran
4- Ph.D. in Epidemiology, Assistant Professor, Health Research Center, Life Style Institute, Baqiyatallah University of Medical Sciences, Tehran, Iran
5- Ph.D. in Virology, Assistant Professor, Medical Microbiology Department, School of Medicine, Baqiyatallah University of Medical Sciences, Tehran, Iran |
|
|
Abstract: (1190 Views) |
Introduction: Neisseria meningitidis is a pathogenic bacterium that settles in the nasopharynx of people. This bacterium has thirteen different serological groups, but the most common groups that play a role in causing the fatal disease of meningitis are serological groups A, B, C, W135 and Y. This disease is of special importance in the military forces and determining and identifying carriers of different serogroups is very important
Objective: This study was conducted to determine the number of carriers of Neisseria meningitidis serological groups using the PCR (Polymerase Chain Reaction) method in students of Baqiyatullah University of Medical Sciences before and after vaccination.
Materials and Methods: This cross-sectional study was conducted on the pharynx samples of 115 students of Baghiyallah University of Medical Sciences in 2019. Sampling was done by Dacron swab from the pharynx. The samples were cultured in a specific and enriching culture medium.After 24 to 48 hours of incubation, biochemical methods were used to determine the identity of the strains. Then, their serological groups were determined by PCR method.
Results: From 115 students, no serogroup of Neisseria Meningitidis was isolated in the stage before the double vaccination of Meningococcal Meningitis (De Vallan Meningococcal A+C).In the post-vaccination stage, two cases of Neisseria Meningitidis were detected among 68 students.
Conclusion: The findings of this research indicate that no serological group was observed in the throat of people before vaccination. While vaccination and when the students were in the dormitory, two cases of Neisseria Meningitidis group C were detected. The observance of health principles, especially the use of masks during the coronavirus pandemic (COVID-19), has influenced the results of this study. It is possible that under normal conditions and the non-implementation of special regulations related to Corona, the number of positive cases after the presence of students in the dormitory is more than the cases identified in this research. |
|
| Keywords: Carriers, Serological Group, Neisseria Meningitidis, Polymerase Chain Reaction |
|
|
Full-Text [PDF 656 kb]
(569 Downloads)
|
Type of Study: Research |
Subject:
bacteriology
Received: 2023/01/22 | Revised: 2023/08/14 | Accepted: 2023/08/15 | Published: 2023/10/2
|
|
|
|
|
|
|
| Send email to the article author |
|
|
|
| Add your comments about this article |
|
|
|
